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Comparative efficacy of a single oral dose of ondansetron and of buspirone against cisplatin-induced emesis in cancer patients.
Buspirone, an agonist of the 5-HT1A subtype of serotonin receptors, has shown antiemetic activity in animal models. However, in cancer patients treated with cisplatin, ondansetron, given either i.v. (one 8-mg dose 30 min after cisplatin) or orally (one 16-mg dose at the end of cisplatin infusion) wa...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1995
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034051/ https://www.ncbi.nlm.nih.gov/pubmed/7547213 |