Pharmacokinetics and binding of the bioreductive probe for hypoxia, NITP: effect of route of administration.

The novel compound 7(-)[4'-(2-nitroimidazol-l-yl)-butyl]-theophylline (NITP) can be used as an immunologically detectable probe for hypoxic cells. Because of the limited water solubility of NITP, it has been administered dissolved in peanut oil with 10% dimethylsulphoxide (DMSO). A new aqueous...

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Detalles Bibliográficos
Autores principales: Hodgkiss, R. J., Stratford, M. R., Dennis, M. F., Hill, S. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034084/
https://www.ncbi.nlm.nih.gov/pubmed/8519660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034084/
https://www.ncbi.nlm.nih.gov/pubmed/8519660

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