An evaluation of hepatic extraction and clearance of doxorubicin.

A swine model was developed to study quantitatively the pharmacokinetics of hepatic extraction and clearance of doxorubicin (DOX). Systemic and hepatic artery infusions of DOX (0.5-9 mg kg-1) were administered to 34 pigs. Pharmacokinetic analysis was simplified by use of a double-balloon catheter in...

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Detalles Bibliográficos
Autores principales: August, D. A., Verma, N., Vaertan, M. A., Shah, R., Brenner, D. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034109/
https://www.ncbi.nlm.nih.gov/pubmed/7599068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034109/
https://www.ncbi.nlm.nih.gov/pubmed/7599068

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