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Efficacy assessment of SNP sets for genome-wide disease association studies

The power of a genome-wide disease association study depends critically upon the properties of the marker set used, particularly the number and physical spacing of markers, and the level of inter-marker association due to linkage disequilibrium. Extending our previously devised theoretical framework...

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Detalles Bibliográficos
Autores principales: Wollstein, Andreas, Herrmann, Alexander, Wittig, Michael, Nothnagel, Michael, Franke, Andre, Nürnberg, Peter, Schreiber, Stefan, Krawczak, Michael, Hampe, Jochen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034459/
https://www.ncbi.nlm.nih.gov/pubmed/17726055
http://dx.doi.org/10.1093/nar/gkm621