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A rapid high-throughput method for the detection and quantification of RNA editing based on high-resolution melting of amplicons
We describe a rapid, high-throughput method to scan for new RNA editing sites. This method is adapted from high-resolution melting (HRM) analysis of amplicons, a technique used in clinical research to detect mutations in genomes. The assay was validated by the discovery of six new editing sites in d...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034463/ https://www.ncbi.nlm.nih.gov/pubmed/17726051 http://dx.doi.org/10.1093/nar/gkm640 |