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Comparative assessment of plasmid and oligonucleotide DNA substrates in measurement of in vitro base excision repair activity
Mammalian base excision repair (BER) is mediated through at least two subpathways designated ‘single-nucleotide’ (SN) and ‘long-patch’ (LP) BER (2-nucleotides long/more repair patch). Two forms of DNA substrate are generally used for in vitro BER assays: oligonucleotide- and plasmid-based. For plasm...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034467/ https://www.ncbi.nlm.nih.gov/pubmed/17720705 http://dx.doi.org/10.1093/nar/gkm639 |