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Comparative assessment of plasmid and oligonucleotide DNA substrates in measurement of in vitro base excision repair activity

Mammalian base excision repair (BER) is mediated through at least two subpathways designated ‘single-nucleotide’ (SN) and ‘long-patch’ (LP) BER (2-nucleotides long/more repair patch). Two forms of DNA substrate are generally used for in vitro BER assays: oligonucleotide- and plasmid-based. For plasm...

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Detalles Bibliográficos
Autores principales: Hou, Esther W., Prasad, Rajendra, Asagoshi, Kenjiro, Masaoka, Aya, Wilson, Samuel H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034467/
https://www.ncbi.nlm.nih.gov/pubmed/17720705
http://dx.doi.org/10.1093/nar/gkm639