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Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules

The human DNA repair protein RAD51 is the crucial component of helical nucleoprotein filaments that drive homologous recombination. The molecular mechanistic details of how this structure facilitates the requisite DNA strand rearrangements are not known but must involve dynamic interactions between...

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Detalles Bibliográficos
Autores principales: van der Heijden, Thijn, Seidel, Ralf, Modesti, Mauro, Kanaar, Roland, Wyman, Claire, Dekker, Cees
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034483/
https://www.ncbi.nlm.nih.gov/pubmed/17709342
http://dx.doi.org/10.1093/nar/gkm629