Cargando…

Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules

The human DNA repair protein RAD51 is the crucial component of helical nucleoprotein filaments that drive homologous recombination. The molecular mechanistic details of how this structure facilitates the requisite DNA strand rearrangements are not known but must involve dynamic interactions between...

Descripción completa

Detalles Bibliográficos
Autores principales:	van der Heijden, Thijn, Seidel, Ralf, Modesti, Mauro, Kanaar, Roland, Wyman, Claire, Dekker, Cees
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034483/ https://www.ncbi.nlm.nih.gov/pubmed/17709342 http://dx.doi.org/10.1093/nar/gkm629

Ejemplares similares

Structural and torsional properties of the RAD51-dsDNA nucleoprotein filament
por: Lee, Mina, et al.
Publicado: (2013)

Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics
por: Li, Xuan, et al.
Publicado: (2007)

Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function
por: Ristic, Dejan, et al.
Publicado: (2005)

Real-time measurements of the nucleation, growth and dissociation of single Rad51–DNA nucleoprotein filaments
por: Miné, Judith, et al.
Publicado: (2007)

Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity
por: Zhang, Xiao-Ping, et al.
Publicado: (2009)

The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
por: Crickard, J Brooks, et al.
Publicado: (2019)

Counting RAD51 proteins disassembling from nucleoprotein filaments under tension
por: van Mameren, Joost, et al.
Publicado: (2008)

The differential extension in dsDNA bound to Rad51 filaments may play important roles in homology recognition and strand exchange
por: Danilowicz, Claudia, et al.
Publicado: (2014)

RAD54 controls access to the invading 3′-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae
por: Li, Xuan, et al.
Publicado: (2009)

Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases
por: Ploquin, Mickaël, et al.
Publicado: (2007)

Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase
por: Chen, Jianhong, et al.
Publicado: (2015)

Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions
por: Konomura, Naoto, et al.
Publicado: (2017)

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
por: Notenboom, Valerie, et al.
Publicado: (2007)

The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates NEIL1 glycosylase
por: Guan, Xin, et al.
Publicado: (2007)

The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
por: Guan, Xin, et al.
Publicado: (2007)

Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques
por: Holthausen, J. T., et al.
Publicado: (2011)

RNA binding to APOBEC3G induces the disassembly of functional deaminase complexes by displacing single-stranded DNA substrates
por: Polevoda, Bogdan, et al.
Publicado: (2015)

Dynamics of RecA filaments on single-stranded DNA
por: van Loenhout, Marijn T. J., et al.
Publicado: (2009)

Genetic and functional interactions between Mus81–Mms4 and Rad27
por: Kang, Min-Jung, et al.
Publicado: (2010)

The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase β in long patch base excision repair
por: Gembka, Agnieszka, et al.
Publicado: (2007)

Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively
por: Burnham, Daniel R., et al.
Publicado: (2017)

Active displacement of RecA filaments by UvrD translocase activity
por: Petrova, Vessela, et al.
Publicado: (2015)

Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence
por: Koster, Daniel A., et al.
Publicado: (2008)

RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange
por: Bonde, Nina J, et al.
Publicado: (2022)

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity
por: Hohl, Marcel, et al.
Publicado: (2007)

Strand-specific effect of Rad26 and TFIIS in rescuing transcriptional arrest by CAG trinucleotide repeat slip-outs
por: Xu, Jun, et al.
Publicado: (2021)

Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments
por: Conover, Alyson J., et al.
Publicado: (2011)

The wobble nucleotide-excising anticodon nuclease RloC is governed by the zinc-hook and DNA-dependent ATPase of its Rad50-like region
por: Klaiman, Daniel, et al.
Publicado: (2012)

DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion
por: Schwarz, Friedrich W., et al.
Publicado: (2011)

Force regulated dynamics of RPA on a DNA fork
por: Kemmerich, Felix E., et al.
Publicado: (2016)

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA
por: Kostiuk, Georgij, et al.
Publicado: (2017)

Single-molecule analysis of 1D diffusion and transcription elongation of T7 RNA polymerase along individual stretched DNA molecules
por: Kim, Ji Hoon, et al.
Publicado: (2007)

Visualizing helicases unwinding DNA at the single molecule level
por: Fili, Natali, et al.
Publicado: (2010)

Probing DNA clamps with single-molecule force spectroscopy
por: Wang, Lin, et al.
Publicado: (2013)

Probing the stability of the SpCas9–DNA complex after cleavage
por: Aldag, Pierre, et al.
Publicado: (2021)

Binding of two DNA molecules by type II topoisomerases for decatenation
por: Kumar, Rupesh, et al.
Publicado: (2012)

A highly processive topoisomerase I: studies at the single-molecule level
por: Szafran, Marcin Jan, et al.
Publicado: (2014)

Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53
por: Rajagopalan, Sridharan, et al.
Publicado: (2011)

Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I
por: Markiewicz, Radoslaw P., et al.
Publicado: (2012)

Single molecule analysis of Thermus thermophilus SSB protein dynamics on single-stranded DNA
por: Zhang, Jichuan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_djr8j3v9i944q1qgke42o4kj51