Human tryptophanyl-tRNA synthetase is switched to a tRNA-dependent mode for tryptophan activation by mutations at V85 and I311

For most aminoacyl-tRNA synthetases (aaRS), their cognate tRNA is not obligatory to catalyze amino acid activation, with the exception of four class I (aaRS): arginyl-tRNA synthetase, glutamyl-tRNA synthetase, glutaminyl-tRNA synthetase and class I lysyl-tRNA synthetase. Furthermore, for arginyl-, g...

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Detalles Bibliográficos
Autores principales: Guo, Li-Tao, Chen, Xiang-Long, Zhao, Bo-Tao, Shi, Yi, Li, Wei, Xue, Hong, Jin, You-Xin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034488/
https://www.ncbi.nlm.nih.gov/pubmed/17726052
http://dx.doi.org/10.1093/nar/gkm633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034488/
https://www.ncbi.nlm.nih.gov/pubmed/17726052
http://dx.doi.org/10.1093/nar/gkm633

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