Cargando…

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood

BACKGROUND: During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients. There are indications, that fever reduces the mortality of seps...

Descripción completa

Detalles Bibliográficos
Autores principales: Sucker, Christoph, Zacharowski, Kai, Thielmann, Matthias, Hartmann, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034544/
https://www.ncbi.nlm.nih.gov/pubmed/17892553
http://dx.doi.org/10.1186/1477-9560-5-13