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Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain
BACKGROUND: The transmembrane presenilin (PSEN) proteins, PSEN1 and PSEN2, have been proposed to be the catalytic components of the γ-secretase protein complex, which is an intramembranous multimeric protease involved in development, cell regulatory processes, and neurodegeneration in Alzheimer'...
Autores principales: | Madsen, Lone B, Thomsen, Bo, Larsen, Knud, Bendixen, Christian, Holm, Ida E, Fredholm, Merete, Jørgensen, Arne L, Nielsen, Anders L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034586/ https://www.ncbi.nlm.nih.gov/pubmed/17854491 http://dx.doi.org/10.1186/1471-2202-8-72 |
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