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Sensitivity and specificity of tritiated thymidine incorporation and ELISPOT assays in identifying antigen specific T cell immune responses

BACKGROUND: Standardization of cell-based immunologic monitoring is becoming increasingly important as methods for measuring cellular immunity become more complex. We assessed the ability of two commonly used cell-based assays, tritiated thymidine incorporation (proliferation) and IFN-gamma ELISPOT,...

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Detalles Bibliográficos
Autores principales: Goodell, Vivian, dela Rosa, Corazon, Slota, Meredith, MacLeod, Beth, Disis, Mary L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034595/
https://www.ncbi.nlm.nih.gov/pubmed/17850666
http://dx.doi.org/10.1186/1471-2172-8-21