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Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae
BACKGROUND: The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature termination codons (PTCs). In yeast Saccharomyces cerevisiae, the activity of the NMD pathway depends on the recognition of the PTC by the translational machinery. Translation term...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039749/ https://www.ncbi.nlm.nih.gov/pubmed/17705828 http://dx.doi.org/10.1186/1471-2199-8-71 |