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Heat Shock Proteins and Amateur Chaperones in Amyloid-Beta Accumulation and Clearance in Alzheimer’s Disease

The pathologic lesions of Alzheimer’s disease (AD) are characterized by accumulation of protein aggregates consisting of intracellular or extracellular misfolded proteins. The amyloid-β (Aβ) protein accumulates extracellularly in senile plaques and cerebral amyloid angiopathy, whereas the hyperphosp...

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Detalles Bibliográficos
Autores principales: Wilhelmus, Micha M. M., de Waal, Robert M. W., Verbeek, Marcel M.
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039847/
https://www.ncbi.nlm.nih.gov/pubmed/17917109
http://dx.doi.org/10.1007/s12035-007-0029-7