Increase of calnexin gene dosage boosts the secretion of heterologous proteins by Hansenula polymorpha

The type I membrane protein calnexin is a conserved key component of the quality control mechanism in the endoplasmic reticulum. It functions as a molecular chaperone that monitors the folding state of nascent polypeptides entering the endoplasmic reticulum. Calnexin also behaves as a lectin, as its...

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Detalles Bibliográficos
Autores principales: Klabunde, Jens, Kleebank, Sebastian, Piontek, Michael, Hollenberg, Cornelis P, Hellwig, Stephan, Degelmann, Adelheid
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040192/
https://www.ncbi.nlm.nih.gov/pubmed/17617219
http://dx.doi.org/10.1111/j.1567-1364.2007.00271.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040192/
https://www.ncbi.nlm.nih.gov/pubmed/17617219
http://dx.doi.org/10.1111/j.1567-1364.2007.00271.x

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