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Persisting benefits 12–18 months after discontinuation of pubertal metformin therapy in low birthweight girls

BACKGROUND: Discontinuation of metformin therapy, if started beyond menarche in adolescents or young women with hyperinsulinaemia following low birthweight, is rapidly followed by rebound deteriorations in body fat, insulin resistance and blood lipid profile. OBJECTIVE: We hypothesized that early co...

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Detalles Bibliográficos
Autores principales: Ong, Ken, de Zegher, Francis, Valls, Carme, Dunger, David B, Ibáñez, Lourdes
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040227/
https://www.ncbi.nlm.nih.gov/pubmed/17608755
http://dx.doi.org/10.1111/j.1365-2265.2007.02952.x