The Novel CXCL12γ Isoform Encodes an Unstructured Cationic Domain Which Regulates Bioactivity and Interaction with Both Glycosaminoglycans and CXCR4

BACKGROUND: CXCL12α, a chemokine that importantly promotes the oriented cell migration and tissue homing of many cell types, regulates key homeostatic functions and pathological processes through interactions with its cognate receptor (CXCR4) and heparan sulfate (HS). The alternative splicing of the...

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Detalles Bibliográficos
Autores principales: Laguri, Cédric, Sadir, Rabia, Rueda, Patricia, Baleux, Françoise, Gans, Pierre, Arenzana-Seisdedos, Fernando, Lortat-Jacob, Hugues
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040504/
https://www.ncbi.nlm.nih.gov/pubmed/17971873
http://dx.doi.org/10.1371/journal.pone.0001110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040504/
https://www.ncbi.nlm.nih.gov/pubmed/17971873
http://dx.doi.org/10.1371/journal.pone.0001110

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