The R403Q Myosin Mutation Implicated in Familial Hypertrophic Cardiomyopathy Causes Disorder at the Actomyosin Interface

BACKGROUND: Mutations in virtually all of the proteins comprising the cardiac muscle sarcomere have been implicated in causing Familial Hypertrophic Cardiomyopathy (FHC). Mutations in the β-myosin heavy chain (MHC) remain among the most common causes of FHC, with the widely studied R403Q mutation re...

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Detalles Bibliográficos
Autores principales: Volkmann, Niels, Lui, HongJun, Hazelwood, Larnele, Trybus, Kathleen M., Lowey, Susan, Hanein, Dorit
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040505/
https://www.ncbi.nlm.nih.gov/pubmed/17987111
http://dx.doi.org/10.1371/journal.pone.0001123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040505/
https://www.ncbi.nlm.nih.gov/pubmed/17987111
http://dx.doi.org/10.1371/journal.pone.0001123

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