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Pilocarpine-Induced Status Epilepticus in Rats Involves Ischemic and Excitotoxic Mechanisms

The neuron loss characteristic of hippocampal sclerosis in temporal lobe epilepsy patients is thought to be the result of excitotoxic, rather than ischemic, injury. In this study, we assessed changes in vascular structure, gene expression, and the time course of neuronal degeneration in the cerebral...

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Detalles Bibliográficos
Autores principales: Fabene, Paolo Francesco, Merigo, Flavia, Galiè, Mirco, Benati, Donatella, Bernardi, Paolo, Farace, Paolo, Nicolato, Elena, Marzola, Pasquina, Sbarbati, Andrea
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040510/
https://www.ncbi.nlm.nih.gov/pubmed/17971868
http://dx.doi.org/10.1371/journal.pone.0001105