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Perturbation of the Dimer Interface of Triosephosphate Isomerase and its Effect on Trypanosoma cruzi
BACKGROUND: Chagas disease affects around 18 million people in the American continent. Unfortunately, there is no satisfactory treatment for the disease. The drugs currently used are not specific and exert serious toxic effects. Thus, there is an urgent need for drugs that are effective. Looking for...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2041813/ https://www.ncbi.nlm.nih.gov/pubmed/17989778 http://dx.doi.org/10.1371/journal.pntd.0000001 |