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A Stochastic View of Spliceosome Assembly and Recycling in the Nucleus

How splicing factors are recruited to nascent transcripts in the nucleus in order to assemble spliceosomes on newly synthesised pre-mRNAs is unknown. To address this question, we compared the intranuclear trafficking kinetics of small nuclear ribonucleoprotein particles (snRNP) and non-snRNP protein...

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Detalles Bibliográficos
Autores principales: Rino, José, Carvalho, Teresa, Braga, José, Desterro, Joana M. P, Lührmann, Reinhard, Carmo-Fonseca, Maria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2041977/
https://www.ncbi.nlm.nih.gov/pubmed/17967051
http://dx.doi.org/10.1371/journal.pcbi.0030201