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Genome-Wide Screen for Modifiers of Ataxin-3 Neurodegeneration in Drosophila
Spinocerebellar ataxia type-3 (SCA3) is among the most common dominantly inherited ataxias, and is one of nine devastating human neurodegenerative diseases caused by the expansion of a CAG repeat encoding glutamine within the gene. The polyglutamine domain confers toxicity on the protein Ataxin-3 le...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2041992/ https://www.ncbi.nlm.nih.gov/pubmed/17953484 http://dx.doi.org/10.1371/journal.pgen.0030177 |