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Genome-Wide Profiling of DNA Methylation Reveals a Class of Normally Methylated CpG Island Promoters

The role of CpG island methylation in normal development and cell differentiation is of keen interest, but remains poorly understood. We performed comprehensive DNA methylation profiling of promoter regions in normal peripheral blood by methylated CpG island amplification in combination with microar...

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Detalles Bibliográficos
Autores principales: Shen, Lanlan, Kondo, Yutaka, Guo, Yi, Zhang, Jiexin, Zhang, Li, Ahmed, Saira, Shu, Jingmin, Chen, Xinli, Waterland, Robert A, Issa, Jean-Pierre J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2041996/
https://www.ncbi.nlm.nih.gov/pubmed/17967063
http://dx.doi.org/10.1371/journal.pgen.0030181