Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site

BACKGROUND: Understanding the interaction between viral proteins and neutralizing antibodies at atomic resolution is hindered by a lack of experimentally solved complexes. Progress in computational docking has led to the prediction of increasingly high-quality model antibody-antigen complexes. The a...

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Detalles Bibliográficos
Autores principales: McKinney, Brett A, Kallewaard, Nicole L, Crowe, James E, Meiler, Jens
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042970/
https://www.ncbi.nlm.nih.gov/pubmed/17877819
http://dx.doi.org/10.1186/1745-7580-3-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042970/
https://www.ncbi.nlm.nih.gov/pubmed/17877819
http://dx.doi.org/10.1186/1745-7580-3-8

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