Systematic In Vivo Analysis of the Intrinsic Determinants of Amyloid β Pathogenicity

Protein aggregation into amyloid fibrils and protofibrillar aggregates is associated with a number of the most common neurodegenerative diseases. We have established, using a computational approach, that knowledge of the primary sequences of proteins is sufficient to predict their in vitro aggregati...

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Detalles Bibliográficos
Autores principales: Luheshi, Leila M, Tartaglia, Gian Gaetano, Brorsson, Ann-Christin, Pawar, Amol P, Watson, Ian E, Chiti, Fabrizio, Vendruscolo, Michele, Lomas, David A, Dobson, Christopher M, Crowther, Damian C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043051/
https://www.ncbi.nlm.nih.gov/pubmed/17973577
http://dx.doi.org/10.1371/journal.pbio.0050290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043051/
https://www.ncbi.nlm.nih.gov/pubmed/17973577
http://dx.doi.org/10.1371/journal.pbio.0050290

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