An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data

BACKGROUND: Protein-protein interactions (PPIs) are challenging but attractive targets for small chemical drugs. Whole PPIs, called the 'interactome', have been emerged in several organisms, including human, based on the recent development of high-throughput screening (HTS) technologies. I...

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Detalles Bibliográficos
Autores principales: Sugaya, Nobuyoshi, Ikeda, Kazuyoshi, Tashiro, Toshiyuki, Takeda, Shizu, Otomo, Jun, Ishida, Yoshiko, Shiratori, Akiko, Toyoda, Atsushi, Noguchi, Hideki, Takeda, Tadayuki, Kuhara, Satoru, Sakaki, Yoshiyuki, Iwayanagi, Takao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045083/
https://www.ncbi.nlm.nih.gov/pubmed/17705877
http://dx.doi.org/10.1186/1471-2210-7-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045083/
https://www.ncbi.nlm.nih.gov/pubmed/17705877
http://dx.doi.org/10.1186/1471-2210-7-10

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