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Drosophila Spd-2 Recruits PCM to the Sperm Centriole, but Is Dispensable for Centriole Duplication

In C. elegans, genome-wide screens have identified just five essential centriole-duplication factors: SPD-2, ZYG-1, SAS-5, SAS-6, and SAS-4 [1–8]. These proteins are widely believed to comprise a conserved core duplication module [3, 9–14]. In worm embryos, SPD-2 is the most upstream component of th...

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Detalles Bibliográficos
Autores principales: Dix, Carly I., Raff, Jordan W.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045633/
https://www.ncbi.nlm.nih.gov/pubmed/17919907
http://dx.doi.org/10.1016/j.cub.2007.08.065