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Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes
Networks of regulatory relations between transcription factors (TF) and their target genes (TG)- implemented through TF binding sites (TFBS)- are key features of biology. An idealized approach to solving such networks consists of starting from a consensus TFBS or a position weight matrix (PWM) to ge...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047340/ https://www.ncbi.nlm.nih.gov/pubmed/17973026 http://dx.doi.org/10.1371/journal.pone.0001115 |