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Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes

Networks of regulatory relations between transcription factors (TF) and their target genes (TG)- implemented through TF binding sites (TFBS)- are key features of biology. An idealized approach to solving such networks consists of starting from a consensus TFBS or a position weight matrix (PWM) to ge...

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Detalles Bibliográficos
Autores principales: Aerts, Stein, van Helden, Jacques, Sand, Olivier, Hassan, Bassem A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047340/
https://www.ncbi.nlm.nih.gov/pubmed/17973026
http://dx.doi.org/10.1371/journal.pone.0001115