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Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

BACKGROUND: The platelet P2Y(12 )receptor plays a key role in platelet activation. The H2 haplotype of the P2Y(12 )receptor gene (P2RY12) has been found to be associated with maximal aggregation response to adenosine diphosphate (ADP) and with increased risk for peripheral arterial disease. No data...

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Detalles Bibliográficos
Autores principales: Cavallari, Ugo, Trabetti, Elisabetta, Malerba, Giovanni, Biscuola, Michele, Girelli, Domenico, Olivieri, Oliviero, Martinelli, Nicola, Angiolillo, Dominick J, Corrocher, Roberto, Pignatti, Pier Franco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048504/
https://www.ncbi.nlm.nih.gov/pubmed/17803810
http://dx.doi.org/10.1186/1471-2350-8-59