Cargando…

Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

BACKGROUND: The platelet P2Y(12 )receptor plays a key role in platelet activation. The H2 haplotype of the P2Y(12 )receptor gene (P2RY12) has been found to be associated with maximal aggregation response to adenosine diphosphate (ADP) and with increased risk for peripheral arterial disease. No data...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavallari, Ugo, Trabetti, Elisabetta, Malerba, Giovanni, Biscuola, Michele, Girelli, Domenico, Olivieri, Oliviero, Martinelli, Nicola, Angiolillo, Dominick J, Corrocher, Roberto, Pignatti, Pier Franco
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048504/ https://www.ncbi.nlm.nih.gov/pubmed/17803810 http://dx.doi.org/10.1186/1471-2350-8-59

Ejemplares similares

Combined Effect of Hemostatic Gene Polymorphisms and the Risk of Myocardial Infarction in Patients with Advanced Coronary Atherosclerosis
por: Martinelli, Nicola, et al.
Publicado: (2008)

Low Levels of Serum Paraoxonase Activities are Characteristic of Metabolic Syndrome and May Influence the Metabolic-Syndrome-Related Risk of Coronary Artery Disease
por: Martinelli, Nicola, et al.
Publicado: (2012)

Hyperhomocysteinemia and Mortality after Coronary Artery Bypass Grafting
por: Girelli, Domenico, et al.
Publicado: (2006)

Additive effect of LRP8/APOER2 R952Q variant to APOE ε2/ε3/ε4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study
por: Martinelli, Nicola, et al.
Publicado: (2009)

Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries
por: Cagnin, Stefano, et al.
Publicado: (2009)

Variants of GCKR Affect Both β-Cell and Kidney Function in Patients With Newly Diagnosed Type 2 Diabetes: The Verona Newly Diagnosed Type 2 Diabetes Study 2
por: Bonetti, Sara, et al.
Publicado: (2011)

CACNA1E Variants Affect Beta Cell Function in Patients with Newly Diagnosed Type 2 Diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 3
por: Trombetta, Maddalena, et al.
Publicado: (2012)

Novel protein-truncating variant in the APOB gene may protect from coronary artery disease and adverse cardiovascular events
por: Mango, Gabriele, et al.
Publicado: (2022)

Access Rate to the Emergency Department for Venous Thromboembolism in Relationship with Coarse and Fine Particulate Matter Air Pollution
por: Martinelli, Nicola, et al.
Publicado: (2012)

High resolution preparation of monocyte-derived macrophages (MDM) protein fractions for clinical proteomics
por: Polati, Rita, et al.
Publicado: (2009)

Factor II Activity is Similarly Increased in Patients With Elevated Apolipoprotein CIII and in Carriers of the Factor II 20210A Allele
por: Olivieri, Oliviero, et al.
Publicado: (2013)

A Preliminary microRNA Analysis of Non Syndromic Thoracic Aortic Aneurysms
por: Patuzzo, C, et al.
Publicado: (2012)

When Less Becomes More: Insights on the Pharmacodynamic Effects of Aspirin Withdrawal in Patients With Potent Platelet P2Y(12) Inhibition Induced by Ticagrelor
por: Capodanno, Davide, et al.
Publicado: (2020)

Evaluation of Hepcidin Isoforms in Hemodialysis Patients by a Proteomic Approach Based on SELDI-TOF MS
por: Campostrini, Natascia, et al.
Publicado: (2010)

Not Just Arterial Damage: Increased Incidence of Venous Thromboembolic Events in Cardiovascular Patients With Elevated Plasma Levels of Apolipoprotein CIII
por: Olivieri, Oliviero, et al.
Publicado: (2019)

Platelet thrombin receptor antagonism and atherothrombosis
por: Angiolillo, Dominick J., et al.
Publicado: (2010)

Imputation reliability on DNA biallelic markers for drug metabolism studies
por: Mijatovic, Vladan, et al.
Publicado: (2012)

Hepcidin Levels and Their Determinants in Different Types of Myelodysplastic Syndromes
por: Santini, Valeria, et al.
Publicado: (2011)

Serum levels of the hepcidin-20 isoform in a large general population: The Val Borbera study()
por: Campostrini, Natascia, et al.
Publicado: (2012)

Tailoring P2Y(12) Inhibiting Therapy in Elderly Patients With Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
por: Capranzano, Piera, et al.
Publicado: (2019)

P2Y(12) Inhibitor Monotherapy after Percutaneous Coronary Intervention
por: Zhou, Xuan, et al.
Publicado: (2022)

Basophil Blood Cell Count Is Associated With Enhanced Factor II Plasma Coagulant Activity and Increased Risk of Mortality in Patients With Stable Coronary Artery Disease: Not Only Neutrophils as Prognostic Marker in Ischemic Heart Disease
por: Pizzolo, Francesca, et al.
Publicado: (2021)

Iron deficiency in the elderly population, revisited in the hepcidin era
por: Busti, Fabiana, et al.
Publicado: (2014)

Increased Serum Hepcidin Levels in Subjects with the Metabolic Syndrome: A Population Study
por: Martinelli, Nicola, et al.
Publicado: (2012)

Correction: Increased Serum Hepcidin Levels in Subjects with the Metabolic Syndrome: A Population Study
por: Martinelli, Nicola, et al.
Publicado: (2013)

Deep vein thrombosis in SARS-CoV-2 pneumonia-affected patients within standard care units: Exploring a submerged portion of the iceberg
por: Pizzolo, Francesca, et al.
Publicado: (2020)

Antiplatelet Therapy in Diabetes: Efficacy and Limitations of Current Treatment Strategies and Future Directions
por: Angiolillo, Dominick J.
Publicado: (2009)

A Novel ALAS2 Missense Mutation in Two Brothers With Iron Overload and Associated Alterations in Serum Hepcidin/Erythroferrone Levels
por: Lira Zidanes, Acaynne, et al.
Publicado: (2020)

MRP4 over-expression has a role on both reducing nitric oxide-dependent antiplatelet effect and enhancing ADP induced platelet activation
por: Guarino, Maria Luisa, et al.
Publicado: (2020)

CD14(+)-Monocytes Exposed to Apolipoprotein CIII Express Tissue Factor
por: Olivieri, Oliviero, et al.
Publicado: (2023)

Clinical risk scores for the early prediction of severe outcomes in patients hospitalized for COVID-19
por: Ageno, Walter, et al.
Publicado: (2021)

De-escalation of antiplatelet therapy in acute coronary syndromes: Why, how and when?
por: Galli, Mattia, et al.
Publicado: (2022)

Unmet needs in the management of acute myocardial infarction: role of novel protease-activated receptor-1 antagonist vorapaxar
por: Cho, Jung Rae, et al.
Publicado: (2014)

Pharmacokinetic–pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients
por: Åstrand, Magnus, et al.
Publicado: (2018)

Clinical Pharmacology and Cardiovascular Safety of Naproxen
por: Angiolillo, Dominick J., et al.
Publicado: (2016)

Impact of Diabetes Mellitus and Chronic Kidney Disease on Cardiovascular Outcomes and Platelet P2Y(12) Receptor Antagonist Effects in Patients With Acute Coronary Syndromes: Insights From the PLATO Trial
por: Franchi, Francesco, et al.
Publicado: (2019)

High Plasma Concentration of Apolipoprotein C-III Confers an Increased Risk of Cerebral Ischemic Events on Cardiovascular Patients Anticoagulated With Warfarin
por: Olivieri, Oliviero, et al.
Publicado: (2022)

P2Y12 platelet inhibition in clinical practice
por: Damman, Peter, et al.
Publicado: (2011)

Evolving paradigms in antithrombotic therapy for anticoagulated patients undergoing coronary stenting
por: Buccheri, Sergio, et al.
Publicado: (2019)

Editorial: Precision medicine for antithrombotic therapy in patients after percutaneous coronary interventions
por: Galli, Mattia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9npd9sgm3p98l6hbd04d3r59gh