The Transcription Factor Mrr1p Controls Expression of the MDR1 Efflux Pump and Mediates Multidrug Resistance in Candida albicans

Constitutive overexpression of the MDR1 (multidrug resistance) gene, which encodes a multidrug efflux pump of the major facilitator superfamily, is a frequent cause of resistance to fluconazole and other toxic compounds in clinical Candida albicans strains, but the mechanism of MDR1 upregulation has...

Descripción completa

Detalles Bibliográficos
Autores principales: Morschhäuser, Joachim, Barker, Katherine S, Liu, Teresa T, Blaß-Warmuth, Julia, Homayouni, Ramin, Rogers, P. David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048531/
https://www.ncbi.nlm.nih.gov/pubmed/17983269
http://dx.doi.org/10.1371/journal.ppat.0030164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048531/
https://www.ncbi.nlm.nih.gov/pubmed/17983269
http://dx.doi.org/10.1371/journal.ppat.0030164

Ejemplares similares