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The Transcription Factor Mrr1p Controls Expression of the MDR1 Efflux Pump and Mediates Multidrug Resistance in Candida albicans

Constitutive overexpression of the MDR1 (multidrug resistance) gene, which encodes a multidrug efflux pump of the major facilitator superfamily, is a frequent cause of resistance to fluconazole and other toxic compounds in clinical Candida albicans strains, but the mechanism of MDR1 upregulation has...

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Detalles Bibliográficos
Autores principales:	Morschhäuser, Joachim, Barker, Katherine S, Liu, Teresa T, Blaß-Warmuth, Julia, Homayouni, Ramin, Rogers, P. David
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048531/ https://www.ncbi.nlm.nih.gov/pubmed/17983269 http://dx.doi.org/10.1371/journal.ppat.0030164

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