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Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein

Nuclear factor kappa B (NF-κB) is a key regulator of the immune response, but in almost the same manner it is involved in induction of inflammation, proliferation and regulation of apoptosis. In the central nervous system activated NF-κB plays a neuroprotective role. While in some neurodegenerative...

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Detalles Bibliográficos
Autores principales: Bourteele, Soizic, Oesterle, Katja, Weinzierl, Andreas O, Paxian, Stephan, Riemann, Marc, Schmid, Roland M, Planz, Oliver
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048569/
https://www.ncbi.nlm.nih.gov/pubmed/17573907
http://dx.doi.org/10.1111/j.1462-5822.2007.00950.x