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Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein
Nuclear factor kappa B (NF-κB) is a key regulator of the immune response, but in almost the same manner it is involved in induction of inflammation, proliferation and regulation of apoptosis. In the central nervous system activated NF-κB plays a neuroprotective role. While in some neurodegenerative...
Autores principales: | Bourteele, Soizic, Oesterle, Katja, Weinzierl, Andreas O, Paxian, Stephan, Riemann, Marc, Schmid, Roland M, Planz, Oliver |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048569/ https://www.ncbi.nlm.nih.gov/pubmed/17573907 http://dx.doi.org/10.1111/j.1462-5822.2007.00950.x |
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