The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin

Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast protein Epe1 stabilises silent chromatin, preventing the oscillation of heterochromatin domains. Epe1 loss leads to two contrasting phenotypes: alleviation o...

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Detalles Bibliográficos
Autores principales: Trewick, Sarah C, Minc, Elsa, Antonelli, Richard, Urano, Takeshi, Allshire, Robin C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048757/
https://www.ncbi.nlm.nih.gov/pubmed/17948055
http://dx.doi.org/10.1038/sj.emboj.7601892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048757/
https://www.ncbi.nlm.nih.gov/pubmed/17948055
http://dx.doi.org/10.1038/sj.emboj.7601892

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