Cargando…

The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin

Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast protein Epe1 stabilises silent chromatin, preventing the oscillation of heterochromatin domains. Epe1 loss leads to two contrasting phenotypes: alleviation o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trewick, Sarah C, Minc, Elsa, Antonelli, Richard, Urano, Takeshi, Allshire, Robin C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048757/ https://www.ncbi.nlm.nih.gov/pubmed/17948055 http://dx.doi.org/10.1038/sj.emboj.7601892

Ejemplares similares

Regulation of ectopic heterochromatin-mediated epigenetic diversification by the JmjC family protein Epe1
por: Sorida, Masato, et al.
Publicado: (2019)

Noncatalytic Function of a JmjC Domain Protein Disrupts Heterochromatin
por: Bao, Kehan, et al.
Publicado: (2019)

Is JmjC Oxygenase Catalysis Limited to Demethylation?**
por: Hopkinson, Richard J, et al.
Publicado: (2013)

JmjC domain proteins modulate circadian behaviors and sleep in Drosophila
por: Shalaby, Nevine A., et al.
Publicado: (2018)

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
por: Williams, Sophie T, et al.
Publicado: (2015)

JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain
por: Yeo, Kok Siong, et al.
Publicado: (2017)

Characterization of Drosophila melanogaster JmjC+N histone demethylases
por: Lloret-Llinares, Marta, et al.
Publicado: (2008)

Chromatin and oxygen sensing in the context of JmjC histone demethylases
por: Shmakova, Alena, et al.
Publicado: (2014)

JmjC histone demethylases act as chromatin oxygen sensors
por: Batie, Michael, et al.
Publicado: (2019)

JmjC Family of Histone Demethylases Form Nuclear Condensates
por: Vicioso-Mantis, Marta, et al.
Publicado: (2022)

Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance
por: Yaseen, Imtiyaz, et al.
Publicado: (2022)

Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8
por: Wang, Chengliang, et al.
Publicado: (2015)

The Cross Marks the Spot: The Emerging Role of JmjC Domain-Containing Proteins in Myeloid Malignancies
por: Staehle, Hans Felix, et al.
Publicado: (2021)

Kinetic and inhibition studies on human Jumonji-C (JmjC) domain-containing protein 5
por: Tumber, Anthony, et al.
Publicado: (2023)

JmjC Domain-Encoding Genes Are Conserved in Highly Regenerative Metazoans and Are Associated with Planarian Whole-Body Regeneration
por: Cao, Ping-Lin, et al.
Publicado: (2019)

Substrate selectivity and inhibition of histidine JmjC hydroxylases MINA53 and NO66
por: Türkmen, Vildan A., et al.
Publicado: (2023)

Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton
por: Li, Yan, et al.
Publicado: (2022)

An Arabidopsis jmjC domain protein protects transcribed genes from DNA methylation at CHG sites
por: Miura, Asuka, et al.
Publicado: (2009)

Evolutionary History and Functional Diversification of the JmjC Domain-Containing Histone Demethylase Gene Family in Plants
por: Ma, Shifeng, et al.
Publicado: (2022)

MoJMJ1, Encoding a Histone Demethylase Containing JmjC Domain, Is Required for Pathogenic Development of the Rice Blast Fungus, Magnaporthe oryzae
por: Huh, Aram, et al.
Publicado: (2017)

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
por: Walport, Louise J., et al.
Publicado: (2016)

Knockdown of a JmjC domain-containing gene JMJ524 confers altered gibberellin responses by transcriptional regulation of GRAS protein lacking the DELLA domain genes in tomato
por: Li, Jinhua, et al.
Publicado: (2015)

Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins
por: Hahn, Phillip, et al.
Publicado: (2008)

Inhibitors of both the N-methyl lysyl- and arginyl-demethylase activities of the JmjC oxygenases
por: Bonnici, Joanna, et al.
Publicado: (2018)

Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic Functions
por: Kwok, Janice, et al.
Publicado: (2017)

The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly
por: Bao, Kehan, et al.
Publicado: (2022)

Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification
por: Kato, Megumi, et al.
Publicado: (2011)

Genome-wide identification, classification and expression analysis of the JmjC domain-containing histone demethylase gene family in maize
por: Qian, Yexiong, et al.
Publicado: (2019)

Genome-wide identification, classification, and expression analysis of the JmjC domain-containing histone demethylase gene family in birch
por: Chen, Bowei, et al.
Publicado: (2021)

A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1
por: Schiller, Rachel, et al.
Publicado: (2014)

Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans
por: Chowdhury, Rasheduzzaman, et al.
Publicado: (2022)

Genome-Wide Analysis of Soybean JmjC Domain-Containing Proteins Suggests Evolutionary Conservation Following Whole-Genome Duplication
por: Han, Yapeng, et al.
Publicado: (2016)

Characterization and Stress Response of the JmjC Domain-Containing Histone Demethylase Gene Family in the Allotetraploid Cotton Species Gossypium hirsutum
por: Zhang, Jie, et al.
Publicado: (2020)

The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations
por: Hancock, Rebecca L, et al.
Publicado: (2017)

The Schizosaccharomyces pombe JmjC-Protein, Msc1, Prevents H2A.Z Localization in Centromeric and Subtelomeric Chromatin Domains
por: Buchanan, Luke, et al.
Publicado: (2009)

Genome-wide identification, classification and expression analysis of the JmjC domain-containing histone demethylase gene family in Jatropha curcas L.
por: Wang, Jie, et al.
Publicado: (2022)

Systematic analysis of JmjC gene family and stress-response expression of KDM5 subfamily genes in Brassica napus
por: He, Xinghui, et al.
Publicado: (2021)

Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
por: Moon, Yunwon, et al.
Publicado: (2022)

Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin
por: Bao, Kehan, et al.
Publicado: (2019)

Catalysis by the JmjC histone demethylase KDM4A integrates substrate dynamics, correlated motions and molecular orbital control
por: Ramanan, Rajeev, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nqekiurh97ouvi3okfnj4c2t6g