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Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study

BACKGROUND: Currently there is no effective treatment available to retard cyst growth and to prevent the progression to end-stage renal failure in patients with autosomal dominant polycystic kidney disease (ADPKD). Evidence has recently been obtained from animal experiments that activation of the ma...

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Detalles Bibliográficos
Autores principales: Serra, Andreas L, Kistler, Andreas D, Poster, Diane, Struker, Marian, Wüthrich, Rudolf P, Weishaupt, Dominik, Tschirch, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central|1 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048941/
https://www.ncbi.nlm.nih.gov/pubmed/17868472
http://dx.doi.org/10.1186/1471-2369-8-13