Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau

Alzheimer's disease (AD) is characterized by the presence of two histopathological hallmarks; the senile plaques, or extracellular deposits mainly composed of amyloid-β peptide (Aβ), and the neurofibrillary tangles, or intraneuronal inclusions composed of hyperphosphorylated tau protein. Since...

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Detalles Bibliográficos
Autores principales: Santa-Maria, Ismael, Hernández, Félix, Del Rio, Joaquín, Moreno, Francisco J, Avila, Jesús
Formato: Texto
Lenguaje:English
Publicado: BioMed Central|1 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048960/
https://www.ncbi.nlm.nih.gov/pubmed/17822548
http://dx.doi.org/10.1186/1750-1326-2-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048960/
https://www.ncbi.nlm.nih.gov/pubmed/17822548
http://dx.doi.org/10.1186/1750-1326-2-17

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