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Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau
Alzheimer's disease (AD) is characterized by the presence of two histopathological hallmarks; the senile plaques, or extracellular deposits mainly composed of amyloid-β peptide (Aβ), and the neurofibrillary tangles, or intraneuronal inclusions composed of hyperphosphorylated tau protein. Since...
Autores principales: | Santa-Maria, Ismael, Hernández, Félix, Del Rio, Joaquín, Moreno, Francisco J, Avila, Jesús |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central|1
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048960/ https://www.ncbi.nlm.nih.gov/pubmed/17822548 http://dx.doi.org/10.1186/1750-1326-2-17 |
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