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New antimetabolites in cancer chemotherapy and their clinical impact.

It is almost 50 years since antimetabolites were first found to have clinical antitumour activity, with Farber's discovery that aminopterin could cause remission in acute leukaemia. In the following 10 years, methotrexate, 6-mercaptopurine and 5-fluorouracil (5-FU) found their way into clinical...

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Detalles Bibliográficos
Autor principal: Kaye, S. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062805/
https://www.ncbi.nlm.nih.gov/pubmed/9717984

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