Cytotoxic effect of the cyclosporin PSC 833 in multidrug-resistant leukaemia cells with increased expression of P-glycoprotein.

Multidrug resistance (MDR) to anti-cancer agents is frequently associated with overexpression of the drug efflux transporter P-glycoprotein (Pgp) in cancer cells, ensuing drug expulsion and maintenance of tolerable intracellular levels of certain cytotoxic drugs. Pgp may also be present in normal ti...

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Detalles Bibliográficos
Autores principales: Lehne, G., Rugstad, H. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063045/
https://www.ncbi.nlm.nih.gov/pubmed/9744497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063045/
https://www.ncbi.nlm.nih.gov/pubmed/9744497

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