The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas.

Antibody-dependent cellular cytotoxicity (ADCC) is considered to be the major mechanism through which tumour cells, upon treatment with anti-tumour MAbs, are eliminated in vivo. However, the relative importance of various parameters that influence the efficacy of ADCC is unclear. Here we present in...

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Detalles Bibliográficos
Autores principales: Velders, M. P., van Rhijn, C. M., Oskam, E., Fleuren, G. J., Warnaar, S. O., Litvinov, S. V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063081/
https://www.ncbi.nlm.nih.gov/pubmed/9716030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063081/
https://www.ncbi.nlm.nih.gov/pubmed/9716030

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