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Genomic loci susceptible to replication errors in cancer cells.

Microsatellite instability due to a deficiency in DNA mismatch repair is characteristic of a replication error (RER) phenotype. This widespread genomic instability is well documented in hereditary non-polyposis colon cancer (HNPCC) as well as subsets of sporadic carcinomas. Features of the RER pheno...

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Detalles Bibliográficos
Autores principales: Krajinovic, M., Richer, C., Gorska-Flipot, I., Gaboury, L., Novakovic, I., Labuda, D., Sinnett, D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063145/
https://www.ncbi.nlm.nih.gov/pubmed/9792139