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In vitro effect of amifostine on haematopoietic progenitors exposed to carboplatin and non-alkylating antineoplastic drugs: haematoprotection acts as a drug-specific progenitor rescue.

We evaluated the protective ability of amifostine on peripheral blood mononuclear cell (PBMC)-derived colony-forming unit (CFU) and PB CD34+ cells which were previously exposed in vitro to etoposide, carboplatin, doxorubicin and taxotere. Amifostine pretreatment protected PBMC-derived CFU from the t...

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Detalles Bibliográficos
Autores principales: Pierelli, L., Scambia, G., Fattorossi, A., Bonanno, G., Battaglia, A., Perillo, A., Menichella, G., Panici, P. B., Leone, G., Mancuso, S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063161/
https://www.ncbi.nlm.nih.gov/pubmed/9792145