Clearance of yttrium-90-labelled anti-tumour antibodies with antibodies raised against the 12N4 DOTA macrocycle.

Radioimmunotherapy (RIT) is currently limited by toxicity to normal tissues as a result of prolonged circulating radioantibody in the blood. In this study, the use of a clearing antibody was investigated (second antibody) in an attempt to reduce blood background levels of [90Y]A5B7 immunoglobulin G...

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Detalles Bibliográficos
Autores principales: Casey, J. L., King, D. J., Pedley, R. B., Boden, J. A., Boden, R., Chaplin, L. C., Dorning, M., Begent, R. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063187/
https://www.ncbi.nlm.nih.gov/pubmed/9823971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063187/
https://www.ncbi.nlm.nih.gov/pubmed/9823971

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