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Absence of somatic alterations of the EB1 gene adenomatous polyposis coli-associated protein in human sporadic colorectal cancers.

The human EB1 gene product was recently found, by a yeast two-hybrid screening, to be associated with the carboxy terminus of the APC (adenomatous polyposis coli) protein, the product of a tumour-suppressor gene thought to act as a gatekeeper in colorectal carcinogenesis. Because virtually all of th...

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Detalles Bibliográficos
Autores principales: Jaïs, P., Sabourin, J. C., Bombled, J., Rougier, P., Lasser, P., Duvillard, P., Bénard, J., Bressac-de Paillerets, B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063196/
https://www.ncbi.nlm.nih.gov/pubmed/9823979