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BRCA1 and BRCA2 in breast cancer families from Wales: moderate mutation frequency and two recurrent mutations in BRCA1.

Mutations in the BRCA1/BRCA2 genes account for varying proportions of breast cancer families studied, and demonstrate considerable variation in mutational spectra coincident with ethnic and geographical diversity. We have screened for mutations in 17 families from Wales with two or more cases of bre...

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Detalles Bibliográficos
Autores principales: Lancaster, J. M., Carney, M. E., Gray, J., Myring, J., Gumbs, C., Sampson, J., Wheeler, D., France, E., Wiseman, R., Harper, P., Futreal, P. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063207/
https://www.ncbi.nlm.nih.gov/pubmed/9836472