DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.

Fifteen human glioma cell lines were examined for their sensitivity to 1,3-bis(chloroethyl)-nitrosourea (BCNU, carmustine) and cis-dichlorodiamminoplatinum (cisplatin), the induction of DNA interstrand cross-linking (DNA-ISC) induced by the two agents and cellular O6-alkylguanine alkyltransferase (A...

Descripción completa

Detalles Bibliográficos
Autores principales: Beith, J., Hartley, J., Darling, J., Souhami, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063317/
https://www.ncbi.nlm.nih.gov/pubmed/9052400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063317/
https://www.ncbi.nlm.nih.gov/pubmed/9052400

Ejemplares similares