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Biodistribution of charged F(ab')2 photoimmunoconjugates in a xenograft model of ovarian cancer.

The effect of charge modification of photoimmunoconjugates (PICs) on their biodistribution in a xenograft model of ovarian cancer was investigated. Chlorin(e6)c(e6) was attached site specifically to the F(ab')2 fragment of the murine monoclonal antibody OC125, directed against human ovarian can...

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Detalles Bibliográficos
Autores principales: Duska, L. R., Hamblin, M. R., Bamberg, M. P., Hasan, T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063388/
https://www.ncbi.nlm.nih.gov/pubmed/9062404