Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein.

Decreased accumulation of the fluorescent dye BCECF [2', 7'-bis-(2-carboxyethyl)-5-(6)- carboxyfluorescein] characterized murine and human multidrug-resistant cell lines overexpressing the multidrug resistance protein (MRP). Indomethacin (10 microM), a known cyclo-oxygenase and glutathione...

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Detalles Bibliográficos
Autores principales: Draper, M. P., Martell, R. L., Levy, S. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063393/
https://www.ncbi.nlm.nih.gov/pubmed/9062400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063393/
https://www.ncbi.nlm.nih.gov/pubmed/9062400

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